Search results for "Activation-induced rigidity"

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Activation-Induced Rigidity in Neurologically and Cognitively Healthy Individuals Aged 18-90 Years: A Cross-Sectional Study.

2021

Background: Rigidity is a key clinical feature of Parkinson’s disease (PD), but in a very early phase of the disease it may be absent and can be enhanced through active movements of the arm contralateral to the one being tested. Objective: To evaluate in a large cohort of neurologically and cognitively healthy (NCH) subjects aged 18–90 years if activation-induced rigidity (AR) is present in all age classes, and if there are biological differences between subjects showing AR (AR+) and not showing AR (AR-). Methods: 2,228 NCH subjects categorized as young adult (18–44 years), adult (45–64 years), elderly (65–74 years), and old/oldest-old (75–90 years) were included in the analysis, and underw…

Adultmedicine.medical_specialtyParkinson's diseaseAdolescentCross-sectional studyAudiologylacunesProdromal phaseYoung AdultCellular and Molecular NeuroscienceLateral ventriclesCognitionAtrophyHumansMedicinehealthy aging subjectscaudate atrophyYoung adultAgedglobal cerebral atrophyAged 80 and overActivation-induced rigiditybusiness.industryBrainParkinson DiseaseMiddle Agedwhite matter hyperintensitiesmedicine.diseaseMagnetic Resonance ImagingHyperintensityCross-Sectional StudiesHealthy individualsSettore MED/26 - NeurologiaNeurology (clinical)Atrophybusiness
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